Led by Senate Finance Committee Chair Ron Wyden, four Democratic senators on Wednesday outlined plans to reduce the costs of prescription drugs after President Donald Trump claimed he would do so—only to allow Big Pharma companies to delay negotiating lower prices and secure “zero commitments” from top executives on making lifesaving medications more affordable for millions of Americans.
“There is no greater fraud than Donald J. Trump when it comes to lower drug prices,” Wyden (D-Ore.) said. “Our doors are wide open to anybody who wants to take the bold next step forward on lowering drug costs for Americans.”
Along with a “flash report” on Trump’s “broken promises” regarding his pledge to bring drug prices down “to levels nobody ever thought was possible,” Wyden sent a Dear Colleague letter to Democratic senators regarding his committee’s plans to follow through with lowering costs.
“Finance Committee minority staff will dedicate substantial time and effort this year to developing the next generation of healthcare solutions that lower costs for American families,” Wyden wrote. “These solutions will rein in Big Pharma’s outrageous price increases, lower costs for consumers, guarantee predictability for patients, and reduce wasteful government spending that pads the profits of big corporations. Alongside the co-signers of this letter, I invite you to be a part of this bold vision.”
The letter, co-signed by Sens. Catherine Cortez Masto (D-Nev.), Peter Welch (D-Vt.), and Ruben Gallego (D-Ariz.), notes that “the only concrete drug pricing policy Trump enacted within the past year was a price hike for the biggest blockbuster cancer drugs on Earth, giving an $8.8 billion windfall to the pharmaceutical industry.”
In contrast, the senators wrote, the Senate Finance Committee will develop policies to incorporate international pricing models into the Medicare drug price negotiation framework, including by allowing Health and Human Services Secretary Robert F. Kennedy Jr. to consider international prices as a factor or penalize drugmakers when pricing for US customers exceeds international benchmarks.
“Democrats are determined to bring prices down, and we’re willing to work with anyone to find concrete ways to do it.”
The committee will also work to end Republican “blockbuster drug bailouts from negotiation,” like the ones included in the One Big Beautiful Bill Act that shielded several high-priced drugs—including the cancer drug Keytruda—from Medicare price negotiations.
“The Republican budget bill contained a nearly $9 billion sweetheart deal that benefits the biggest drug companies by delaying or exempting some lifesaving medications from negotiation,” reads the Democrats’ flash report.
Gallego said that “when Big Pharma gets richer off the back of a grandmother struggling to pay for cancer medication, the system is broken.”
“That’s what this is all about: Big Pharma execs sitting in their fancy corner offices profiting off of sick, working-class Americans,” the senator said. “We are not going to accept an America where millions of families live in fear of getting sick and needing to fill a prescription. We are going to fight and fight hard for a healthcare system that does what Donald Trump never did: actually lower costs for working families.”
The lawmakers emphasized that even if manufacturers are forced to lower drug prices, patients are not currently guaranteed to directly benefit, because as much as 45% of the $5.4 trillion the US spends on healthcare annually is “absorbed by middlemen such as insurers, pharmacy benefit managers (PBMs), and drug distributors.”
“Healthcare middlemen profit when drug costs are high because they make money off of drug margin or payments that are linked to the price of a drug, ripping off patients who pay more than they should. Medicare Part D and the patients it serves should stop footing the bill for inflated drug prices and instead pay for drugs in a more transparent manner that reduces middleman margin,” wrote the senators.
The Finance Committee will develop policies to eliminate abuses in the prescription drug supply chain including “egregious drug price markups,” and to ensure that patient cost-sharing on drugs more closely aligns with the costs to plans and PBMs.
Finally, the Democrats said they would work to fix the “unmitigated disaster” that Trump and Kennedy have been “for innovation and drug development,” as the administration has proposed slashing the National Institutes of Health budget by 40% and has cut off access to treatment for an estimated 74,000 patients who were enrolled in NIH clinical trials.
The Finance Committee, they said, plans to create new incentives for innovation and drug development, including through the tax code.
In their flash report, the Democrats wrote that while failing to force Big Pharma to the negotiating table to save money for Americans, Trump “has been parading Big Pharma executives through the White House, claiming to be cutting cost-saving deals with these corporations.”
“One look under the hood reveals the truth: Trump is giving them a pass on tariffs, while receiving zero commitments about how they will lower costs for taxpayers and patients,” they wrote. “Donald Trump is getting fleeced by Big Pharma CEOs, and Americans are going to foot the bill.”
Welch said that the president “loves to talk a big game and make promises to working families about lowering prescription drug prices. But in reality, his administration is handling this like a PR problem: They’ve got to keep moving and talking about it, but then do nothing to really address the crisis.”
“Democrats are determined to bring prices down, and we’re willing to work with anyone to find concrete ways to do it,” said Welch. “We’re going to lower healthcare costs and ensure everyone can access affordable, lifesaving, and pain-relieving medication.”

